intervillussrummet

The intervillussrummet, also known as the intervillous space, is a critical component of the maternal side of the placenta. It is a large, irregular space filled with maternal blood that surrounds the chorionic villi, which are finger-like projections from the fetal placenta. This space is essential for facilitating the exchange of nutrients, oxygen, and waste products between the mother and the fetus.

Maternal arteries open directly into the intervillussrummet, releasing oxygenated blood. This blood then flows around the villi, allowing for diffusion of oxygen and nutrients into the fetal capillaries within the villi. Simultaneously, deoxygenated blood and waste products from the fetus diffuse from the fetal capillaries into the intervillussrummet and are then carried away by maternal veins.

The intervillussrummet is lined by the syncytiotrophoblast, the outer layer of the chorionic villi, which directly interfaces with the maternal blood. This remarkable structure ensures efficient and continuous exchange throughout pregnancy. Hemorrhage into the intervillussrummet is a significant clinical concern, as it can impact fetal well-being. The volume of blood within the intervillussrummet is relatively small but is constantly replenished.