immuunkomplekse

Immuunkomplekse, also known as immune complexes, are aggregates of antibodies and their corresponding antigens that form in the body. They are a normal part of the immune response, but when they accumulate in tissues, they can lead to various diseases. Immune complexes are formed when antibodies bind to antigens, such as bacteria, viruses, or other foreign substances, in a way that allows multiple antibodies to attach to a single antigen. This creates a complex that can be large enough to be recognized by the immune system.

The formation of immune complexes is a crucial part of the immune response, as it helps to clear pathogens from the body. However, when immune complexes persist in tissues, they can activate the complement system, leading to inflammation and tissue damage. This can result in a variety of diseases, including rheumatoid arthritis, systemic lupus erythematosus, and vasculitis.

The diagnosis of immune complex diseases often involves laboratory tests that detect the presence of immune complexes in the blood or urine. Treatment typically focuses on managing symptoms and reducing inflammation, although there is no cure for these conditions. Understanding the role of immune complexes in disease can help in the development of new therapies and a better understanding of the immune system.