ickespecifikbindning
Ickespecifikbindning, also known as non-specific binding, refers to the interaction between a ligand and a receptor or binding site that is not mediated by a specific, high-affinity interaction. This type of binding is characterized by a low affinity and specificity, meaning that the ligand can bind to multiple receptors or binding sites with similar affinity. Non-specific binding can occur due to various factors, including electrostatic interactions, hydrophobic interactions, and van der Waals forces, which are relatively weak compared to the specific interactions that occur in high-affinity binding.
Non-specific binding is often considered a nuisance in biological and pharmacological research, as it can interfere
To distinguish between specific and non-specific binding, researchers often use techniques such as competition binding assays,