hgh1

hgh1 is a label that appears in some biological data sets and publications, but it is not a standard gene symbol used consistently across major nomenclature databases. In practice, its interpretation is highly context dependent: in some records it is an alias for GH1, the human growth hormone gene; in others it may denote a locus in a particular genome assembly or refer to a hypothetical or organism-specific gene designated by the authors.

When hgh1 is used as a stand-in for GH1, it refers to the gene that encodes growth hormone, a peptide hormone produced by anterior pituitary cells. The growth hormone precursor is processed to a mature hormone that acts primarily through the growth hormone receptor to stimulate production of IGF-1 in the liver and other tissues, promoting growth and regulating metabolism. GH1 expression is governed by hypothalamic releasing and feedback hormones, notably GHRH and somatostatin, and is subject to developmental and nutritional regulation. Clinical relevance includes growth hormone deficiency, and conditions such as acromegaly or gigantism resulting from excess secreted GH, as well as the therapeutic use of recombinant human growth hormone for pediatric and adult conditions.

In non-human contexts, hgh1 may refer to a species-specific homolog or to a noncanonical gene model; interpretation depends on the source. For precise usage, consult authoritative databases such as HGNC, Ensembl, or NCBI Gene and review accompanying metadata to determine the intended symbol and function.