hemostatice

Hemostatics are agents used to stop bleeding. They work through various mechanisms to promote blood clot formation or physically impede blood flow. These agents can be applied topically to a wound site or administered internally.

Topical hemostatics are often used in surgical procedures to control bleeding from tissues or vessels. They can be derived from natural sources, such as cellulose or gelatin, or be synthetic in nature. Some hemostatics act by providing a surface for platelets to aggregate, while others absorb fluid from the blood, concentrating clotting factors and enhancing clot formation. Certain hemostatic agents also have hemostatic properties, meaning they constrict blood vessels.

Internal hemostatics are typically administered orally or intravenously and are used to manage systemic bleeding disorders. These medications often work by replacing or activating clotting factors that are deficient in the patient's blood. Examples include vitamin K, which is essential for the synthesis of several clotting factors, and desmopressin, which can increase levels of factor VIII and von Willebrand factor.

The choice of hemostatic agent depends on the type and severity of bleeding, as well as the clinical context. They are an important class of medical products used to manage hemorrhage in a wide range of situations.