hematoxylíneozín

Hematoxylin and eosin, often abbreviated as H&E, is the most widely used stain in histology. It is a differential stain, meaning it stains different cellular components in distinct colors, allowing for the visualization of tissue structure under a microscope. Hematoxylin, a natural dye derived from the logwood tree, stains cell nuclei blue. It is a basic dye that binds to acidic molecules within the cell, primarily the nucleic acids in the nucleus. Eosin, an acidic dye, stains the cytoplasm and extracellular matrix pink. It binds to basic molecules, such as proteins, in these cellular compartments. The combination of these two stains provides excellent contrast and detail, making it indispensable for routine pathological examination. H&E staining is a relatively simple and inexpensive technique, contributing to its widespread adoption. Variations in staining intensity and hue can sometimes indicate cellular abnormalities or disease processes. This technique is fundamental for diagnosing a vast array of conditions, from cancer to infectious diseases, by allowing pathologists to assess cellular morphology and tissue architecture.