gyógyszermonitorozás

Gyógyszermonitorozás, often translated as therapeutic drug monitoring (TDM), is the clinical practice of measuring specific drug concentrations in a patient's bloodstream at designated intervals. The primary goal of gyógyszermonitorozás is to optimize drug therapy by ensuring that the drug concentration remains within the therapeutic range, which is the concentration that provides the desired clinical effect without causing undue toxicity. This is particularly important for drugs that have a narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small.

The process typically involves collecting a blood sample from the patient at a specific time relative to their last dose. This sample is then sent to a laboratory for analysis, where the concentration of the drug is determined. The results are then interpreted by a healthcare professional, usually a physician or pharmacist, who uses this information to adjust the patient's medication regimen. Adjustments can include altering the dose, the frequency of administration, or even switching to a different medication if necessary.

Gyógyszermonitorozás is valuable for a variety of medications, including certain antibiotics, anticonvulsants, immunosuppressants, and cardiac drugs. It helps to personalize treatment, improve patient outcomes, reduce the risk of adverse drug reactions, and prevent treatment failure. Factors influencing drug concentrations in the body include patient-specific characteristics like age, weight, kidney and liver function, as well as drug interactions and adherence to the prescribed regimen. Therefore, gyógyszermonitorozás provides crucial objective data to guide effective and safe pharmacotherapy.