granulomatiske
Granulomatiske (granulomatous) is a term used in medicine to describe processes in which granulomas form. A granuloma is an organized collection of immune cells, typically macrophages that have transformed into epithelioid cells, often accompanied by multinucleated giant cells and surrounded by lymphocytes. Fibroblasts and connective tissue may be present as well. Granulomas arise as a persistent immune response to a antigen or irritant that is difficult to eradicate.
Morphologically, granulomas can be non-necrotizing or necrotizing. Non-necrotizing granulomas lack central tissue death, as seen in
Common causes include infectious and noninfectious etiologies. Infectious causes encompass Mycobacterium tuberculosis and other mycobacteria, histoplasma
Diagnosis relies on tissue biopsy with histological examination, aided by special stains and cultures, molecular tests,