glycinebinding
Glycinebinding refers to the interaction in which the amino acid glycine binds to a biological macromolecule, usually through noncovalent contacts, to influence signaling, metabolism, or catalysis. This term encompasses binding events in receptors, enzymes, and transport proteins across organisms and tissues.
In neurobiology, glycine binding is central to inhibitory neurotransmission and modulation of excitatory signaling. The glycine
Binding characteristics are governed by pocket geometry and residue interactions, including hydrogen bonds and ionic contacts,
Methods to study glycinebinding include isothermal titration calorimetry, surface plasmon resonance, X-ray crystallography, cryo-electron microscopy, and