glialimmunemediated
Glial immune mediated refers to processes in which glial cells coordinate immune responses within the nervous system. The concept emphasizes the roles of resident glia—microglia and astrocytes in the central nervous system—as well as peripheral glia such as Schwann cells in nerve injury and repair. It describes how glial cells detect damage or infection and shape subsequent inflammation and clearance of debris.
Key players are microglia, the CNS's intrinsic immune cells, and astrocytes. Microglia sense pathogens or damage
In health, glial immune activity supports debris clearance and tissue remodeling. In disease, dysregulated glial responses
Research on glial immune mediation seeks therapies that preserve protective glial functions while limiting harmful inflammation.