fuchsine

Fuchsine, also known as basic fuchsine or fuchsin, is a magenta-colored dye in the triarylmethane family. It is typically sold as salts such as basic fuchsine or fuchsine hydrochloride and exists as a cationic dye that binds to negatively charged cellular components. The compound has a long history as a dye and staining agent and has been used in various laboratory and textile applications.

In microbiology and histology, fuchsine is best known as a component of carbol fuchsin, the primary stain in the Ziehl-Neelsen acid-fast staining method used to detect Mycobacterium species. After decolorization with acid-alcohol, a counterstain such as methylene blue is applied. Basic fuchsine has also been employed as a general stain in certain histological procedures and, in some contexts, as a dye for laboratory reagents and kits. It has historically served as a textile dye in various markets as well.

Safety considerations: Fuchsine is a toxic dye that can irritate the skin, eyes, and respiratory tract. It should be handled with appropriate protective equipment and in a well-ventilated area. Waste must be disposed of according to local regulations due to environmental and health concerns associated with aromatic dyes.

See also: Carbol fuchsin; Ziehl-Neelsen stain; Triarylmethane dyes; Rosaniline.