fotoszenzibilizáló

Fotoszenzibilizierend is a German term that translates to photosensitizing in English. It describes a substance or treatment that increases the sensitivity of the skin or other tissues to light, particularly ultraviolet (UV) radiation. When a photosensitizing agent is present, exposure to light can trigger a photochemical reaction that would not occur, or would occur to a lesser extent, in its absence. This reaction can lead to various effects, most commonly skin reactions.

Photosensitizing agents can be broadly categorized into two types: endogenous and exogenous. Endogenous photosensitizers are produced within the body, such as certain metabolic byproducts or naturally occurring compounds that accumulate in the skin under specific conditions. Exogenous photosensitizers are substances that are introduced from outside the body, including certain medications, topical preparations, and even some natural compounds found in plants.

The consequences of photosensitization depend on the specific agent, the intensity and duration of light exposure, and individual susceptibility. The most common adverse effect is an exaggerated sunburn-like reaction, characterized by redness, pain, and blistering. This is known as phototoxic reaction. In some cases, a different type of reaction called photoallergic reaction can occur, which involves an immune response and may manifest as eczema-like rashes. Photosensitization is a known side effect of certain drugs, and patients are often advised to protect themselves from direct sunlight when taking these medications.