farmakokineetilised
Farmakokineetilised refers to the study of how a drug moves through the body over time. It encompasses four primary processes: absorption, distribution, metabolism, and excretion, often collectively known as ADME. Absorption describes the process by which a drug enters the bloodstream from its site of administration. Distribution concerns how the drug spreads throughout the body's tissues and fluids. Metabolism, also known as biotransformation, is the chemical alteration of the drug by the body, typically by enzymes, often making it easier to eliminate. Excretion is the removal of the drug and its metabolites from the body, primarily through the kidneys in urine, but also via bile, feces, or exhaled air. Understanding these farmakokineetilised processes is crucial in pharmacology and medicine to determine appropriate dosages, dosing intervals, and routes of administration for medications, ensuring both efficacy and safety. It helps predict how long a drug will remain active in the body and at what concentrations it will be present in different organs.