elastix
Elastix is an open-source software package for medical image registration. It is designed to align images acquired under different conditions, times, or modalities, and supports two- and three-dimensional data. The toolbox provides rigid, affine, and deformable (nonrigid) registration, including B-spline based transforms for flexible alignment.
The software is built on the ITK framework and follows a modular pipeline approach. Registration workflows
Elastix operates in two main stages. Elastix performs the registration and outputs a transform parameter file
Applications and availability: Elastix is widely used in medical imaging research for tasks such as atlas-based