diketopiperazinetype
Diketopiperazine-type refers to a class of cyclic dipeptides characterized by a six-membered ring containing two amide bonds. These structures are formed from the condensation of two amino acids, with the loss of two molecules of water. The basic diketopiperazine structure consists of a central ring with two carbonyl groups and two nitrogen atoms, and varying side chains attached to the carbon atoms adjacent to the nitrogen atoms, derived from the original amino acids.
These compounds are found in nature, often as secondary metabolites produced by bacteria and fungi. They exhibit
The synthesis of diketopiperazines can occur through various methods, including direct cyclization of dipeptides, often facilitated