dermaseptins
Dermaseptins are a family of antimicrobial peptides found in the skin secretions of amphibians, particularly frogs. These peptides are part of the innate immune system, acting as a first line of defense against invading pathogens like bacteria, fungi, and viruses. Dermaseptins are characterized by their cationic nature and their propensity to form amphipathic structures, which allow them to interact with and disrupt the lipid membranes of microbial cells.
The mechanism of action for dermaseptins generally involves pore formation within the microbial cell membrane. Once
Research into dermaseptins is driven by their potent antimicrobial activity and their specificity for microbial cells