deoksykortykosteron

Deoxycorticosterone, often abbreviated as DOC, is a steroid hormone belonging to the mineralocorticoid class. It is primarily produced by the zona glomerulosa of the adrenal cortex. Deoxycorticosterone plays a significant role in regulating electrolyte balance, particularly sodium and potassium levels, within the body. Its main action is on the kidneys, where it promotes the reabsorption of sodium ions and the excretion of potassium ions. This leads to increased water retention and, consequently, an elevation in blood pressure.

While deoxycorticosterone is a naturally occurring hormone, it can also be synthesized for medical purposes. It is sometimes used to treat certain conditions characterized by insufficient adrenal hormone production, such as Addison's disease, where it helps to restore normal electrolyte balance and blood pressure. However, its use requires careful monitoring due to potential side effects like hypertension and edema. Deoxycorticosterone is a precursor to aldosterone, the most potent mineralocorticoid, and while it possesses some mineralocorticoid activity itself, it is generally less potent than aldosterone. The body's production and regulation of deoxycorticosterone are influenced by the renin-angiotensin-aldosterone system and the body's overall fluid and electrolyte status.