degG1v

degG1v is a designation used in genomic annotations to refer to a variant form of the degG1 gene. The “v” indicates a variant sequence distinct from the reference degG1, typically identified in comparative genomics and metagenomic datasets. The degG1 gene is associated with a putative oxidoreductase enzyme family and is found within bacterial genomes.

degG1v is a putative gene variant identified in bacterial genomes, representing a divergent form of the degG1 gene. The variant often appears in draft genome assemblies and metagenomic contigs, where annotation pipelines assign degG1v to open reading frames bearing homology to degG1 but with notable sequence differences.

Gene and protein features: degG1v codes for a predicted enzyme within the degG1-associated oxidoreductase family. Compared to the reference degG1 protein, degG1v sequences show substitutions in conserved motifs near the active site and cofactor-binding region. Protein length is typically 320–380 amino acids; predicted cytosolic localization; nearby genes often include degG1 and regulatory elements.

Function and evidence: There is currently limited experimental evidence for degG1v enzymatic activity. Functional inference relies on sequence similarity and domain analysis to the degG1 family; predictions suggest involvement in oxidation-reduction steps of carbohydrate or secondary-metabolite metabolism, but substrate specificity remains uncertain.

Evolution and distribution: degG1v sequences have been reported in multiple bacterial lineages and tend to form a distinct subclade in phylogenetic analyses, consistent with lineage-specific diversification. The ecological and physiological roles of degG1v are not established.

Status and references: degG1v is a predicted, poorly characterized variant used in annotation pipelines. Further experimental validation, including gene expression and enzymatic assays, would be needed to define its function and significance.