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Decarboxylation is a chemical reaction that removes a carboxyl group from a molecule by releasing it as carbon dioxide (CO2). This process is fundamental in organic chemistry and plays a crucial role in various biological and industrial processes. The carboxyl group (-COOH) is a functional group consisting of a carbonyl group (C=O) and a hydroxyl group (-OH). During decarboxylation, the carbon atom of the carboxyl group breaks its bond with the rest of the molecule, and this carbon then combines with the oxygen from the hydroxyl group to form a molecule of carbon dioxide. The remaining part of the original molecule is typically an alkane or an alkene, depending on the specific reaction.
Decarboxylation can occur through various mechanisms, often facilitated by heat, enzymes, or specific catalysts. For instance,