deacetilázok
Deacetylases are a class of enzymes that play a crucial role in various biological processes by removing acetyl groups from proteins, histones, and other substrates. These enzymes are part of the larger family of lysine deacetylases (KDACs), which are involved in the regulation of gene expression, DNA repair, and cellular differentiation. Deacetylases are classified into several families, including the histone deacetylases (HDACs), sirtuins, and other lysine deacetylases.
Histone deacetylases are a well-studied subclass of deacetylases that specifically target histones, the proteins that package
Sirtuins, another subclass of deacetylases, are known for their involvement in longevity and metabolic regulation. They
Other lysine deacetylases include the KAT2B and KAT8 enzymes, which are involved in the acetylation of histones
Deacetylases are increasingly recognized as important therapeutic targets in various diseases, including cancer, neurodegenerative disorders, and