cyclodextrineillä

Cyclodextrins are a family of cyclic oligosaccharides derived from starch. They are characterized by a toroidal (doughnut-shaped) structure, with a hydrophilic exterior and a hydrophobic interior cavity. This unique structure allows cyclodextrins to form inclusion complexes with a wide range of guest molecules, encapsulating them within their cavities. The size of the cavity varies depending on the number of glucose units in the ring, with common forms including alpha-, beta-, and gamma-cyclodextrins containing six, seven, and eight glucose units, respectively.

The ability of cyclodextrins to complex with other molecules has led to their widespread use in various applications. In the pharmaceutical industry, they are employed to enhance the solubility, stability, and bioavailability of poorly soluble drugs. They can also mask unpleasant tastes and reduce drug irritation. In the food industry, cyclodextrins are used to stabilize flavors and fragrances, reduce cholesterol, and control the release of active ingredients. They also find applications in cosmetics, textiles, and environmental remediation, such as in the removal of pollutants. The safety profile of cyclodextrins, particularly beta-cyclodextrin and its derivatives, has been extensively studied, and they are generally considered safe for use in many applications.