collesin

Collesin is a protein found in humans and other mammals. It is encoded by the CLEC16A gene. This protein plays a role in the immune system and is thought to be involved in the regulation of inflammation. Research suggests that collesin may interact with other proteins to modulate cellular responses to pathogens.

The exact function of collesin is still an active area of scientific investigation. However, studies have linked variations in the CLEC16A gene to an increased risk of developing certain autoimmune diseases, such as type 1 diabetes and Hashimoto's thyroiditis. This association suggests that collesin's role in immune regulation is critical for maintaining self-tolerance.

Collesin is expressed in various immune cells, including macrophages and dendritic cells. Its presence in these cells indicates its importance in initiating and controlling immune responses. Further research aims to elucidate the specific molecular mechanisms by which collesin influences immune cell function and contributes to disease pathogenesis. Understanding collesin's precise role could potentially lead to new therapeutic strategies for autoimmune disorders.