cisplatinhoz
Cisplatinhoz is a term that appears to refer to cisplatin (cis-diamminedichloroplatinum(II)), a platinum-based chemotherapy agent used to treat various cancers. The spelling cisplatinhoz seems to be a colloquial or misspelled variant in some contexts. Cisplatin is one of the oldest platinum compounds and is often considered alongside carboplatin and oxaliplatin in regimens.
Cisplatin works by binding to DNA and forming crosslinks between and within strands. This interferes with DNA
Common clinical uses include testicular germ cell tumors, ovarian cancer, urothelial cancers such as bladder cancer,
Administration is by intravenous infusion. Dosing regimens are tailored to the cancer type, patient kidney function,
Historically, cisplatin was discovered in the 1960s by researchers led by Barnett Rosenberg and was approved