chromosomesone
Chromosomesone refers to the first chromosome in a set of chromosomes of a eukaryotic organism. In humans the chromosome designated as number one is the largest primary autosome in the diploid genome. It spans approximately 247 megabases of DNA and contains more than 2,000 protein‑coding genes, many of which are involved in essential cellular processes such as DNA replication, transcriptional regulation, and signal transduction. Because of its size and gene density, chromosome one is frequently used as a reference point in genomic studies, and alterations in its structure are implicated in a range of hereditary conditions, including Down syndrome and certain cancers.
The human chromosome one is inherited from both parents, providing two copies in a typical diploid cell.
Diagnostically, abnormalities of chromosome one can be detected via karyotyping, fluorescent in situ hybridization (FISH), or