capto

Capto is a brand line of chromatography media marketed by Cytiva (formerly GE Healthcare) used in biopharmaceutical purification. The Capto family comprises resin-based media designed for protein and biomolecule purification across laboratory to manufacturing scales. The line encompasses several chemistries, including ion-exchange, hydrophobic interaction, and mixed-mode concepts, aimed at enabling flexible purification strategies.

Representative Capto resins include Capto Q, a strong anion-exchange resin, and Capto S, a strong cation-exchange resin, as well as Capto Adhere, a hydrophobic interaction resin. The collection also includes Capto Core and Capto MMC, which employ core-shell and multimodal principles to combine size-based separation with ligand-based binding. This variety allows users to choose resins tailored to capture, polish, or deplete specific impurities in different workflows.

Capto media are designed for high binding capacities, robust performance across broad pH and salt ranges, and compatibility with standard chromatography equipment. They are used in a range of applications, from small-scale research Purifications to large-scale manufacturing processes, often as part of multi-step purification schemes to achieve desired purity and yield. The Capto line is documented in Cytiva’s product literature and widely employed in bioprocess development and production workflows.