cGMPhidrolízisre
cGMPhidrolízisre refers to the hydrolysis of cyclic guanosine monophosphate (cGMP). cGMP is a cyclic nucleotide that plays a crucial role as a second messenger in various cellular signaling pathways. These pathways are involved in a wide range of physiological processes, including smooth muscle relaxation, neurotransmission, and photoreception. The hydrolysis of cGMP is the process by which the molecule is broken down into its linear form, guanosine monophosphate (GMP). This breakdown is essential for terminating the signaling cascade initiated by cGMP, allowing the cell to reset and respond to new stimuli.
The enzyme primarily responsible for cGMP hydrolysis is phosphodiesterase (PDE). There are several subtypes of phosphodiesterases,