bdinamasis
bdinamasis is a term that emerged within the field of comparative genomics to describe a specific class of regulatory elements found in the genomes of a subset of vertebrates. The name derives from the Latin words "bioderma" (biological skin) and the Greek "masis" (means or method), reflecting the concept that these sequences act as biological “skins” that regulate gene expression across multiple tissues. Researchers first identified bdinamassis elements while mapping transcription factor binding sites in the developing embryonic tissues of zebrafish and mouse models. They noted that these elements were consistently present in regions controlling developmental genes and exhibited highly conserved motifs across species.
Early functional assays showed that bdinamassis elements act as enhancers, enabling fine‐tuned temporal and spatial expression
Because bdinamassis elements are evolutionarily conserved, they are now used as markers for comparative analyses seeking