antistoffreaksjoner
Antistoffreaksjoner, also known as antibody-mediated reactions, are immune responses in which antibodies bind to a target antigen, leading to a downstream effect. These reactions are fundamental to many therapeutic and diagnostic procedures that involve biologics, such as monoclonal antibody drugs, vaccines, and blood products. The binding of an antibody to its target can trigger a range of physiological events, including complement activation, cell-mediated cytotoxicity, or the release of inflammatory mediators.
There are two broad categories of antistoffreaksjoner. Immediate-type reactions occur within minutes to an hour after
Clinical recognition of antistoffreaksjoner is essential for patient safety. Diagnostic work‑up may involve serum tryptase levels,
Prevention focuses on careful patient screening and monitoring. Genetic or environmental predispositions to hypersensitivity can guide