antireszorptív

Antiresorptive is a term used in medicine, particularly in the context of bone health and certain pharmaceutical treatments. It describes a substance or agent that inhibits or reduces the process of bone resorption. Bone resorption is a natural physiological process where specialized cells called osteoclasts break down bone tissue. This process is essential for bone remodeling, which involves the removal of old bone and the formation of new bone, maintaining bone strength and mineral balance.

In certain medical conditions, such as osteoporosis, the rate of bone resorption can exceed the rate of bone formation, leading to a decrease in bone density and an increased risk of fractures. Antiresorptive medications are therefore prescribed to slow down or stop this excessive bone breakdown. By reducing bone resorption, these agents help to preserve bone mass and reduce the likelihood of skeletal fragility.

Common examples of antiresorptive drugs include bisphosphonates, denosumab, and hormone replacement therapy in some contexts. These medications work through various mechanisms to interfere with the activity of osteoclasts or to induce their programmed cell death. They are a cornerstone of treatment for osteoporosis and other conditions characterized by bone loss. The effectiveness and specific use of antiresorptive agents are determined by a healthcare professional based on individual patient needs and medical history.