antiagregantes

Antiaggregants are a class of drugs used to prevent blood clots from forming or to dissolve existing clots. They are commonly used in the treatment of cardiovascular diseases, such as angina, myocardial infarction, and stroke. Antiaggregants work by inhibiting the aggregation of platelets, which are small blood cells that play a crucial role in blood clotting.

The most well-known antiaggregants are aspirin and the thienopyridines, which include clopidogrel and prasugrel. Aspirin works by inhibiting the enzyme cyclooxygenase, which is involved in the production of thromboxane A2, a potent platelet aggregator. Thienopyridines, on the other hand, directly inhibit the activation of platelets by blocking the P2Y12 receptor.

Antiaggregants are typically used in combination with other medications, such as anticoagulants, to manage blood clotting disorders. They are also used in the prevention of blood clots in patients with certain medical conditions, such as atrial fibrillation and deep vein thrombosis.

While antiaggregants are generally safe and effective, they can cause side effects, including gastrointestinal bleeding, allergic reactions, and increased risk of bleeding. Therefore, they should be used under the guidance of a healthcare professional.