ampicillinasulbactam

Ampicillin/sulbactam is a combination antibiotic medication used to treat a variety of bacterial infections. Ampicillin is a penicillin-type antibiotic that works by inhibiting the synthesis of bacterial cell walls, leading to cell lysis and death. Sulbactam is a beta-lactamase inhibitor that enhances the effectiveness of ampicillin by preventing bacterial enzymes from breaking down the antibiotic. This combination is particularly useful against bacteria that produce beta-lactamase enzymes, which can degrade penicillin antibiotics.

Ampicillin/sulbactam is commonly used to treat infections caused by susceptible bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae. It is often prescribed for severe infections such as pneumonia, meningitis, and skin infections. The medication is available in various forms, including intravenous, oral, and injectable suspensions.

The typical dosage of ampicillin/sulbactam varies depending on the type of infection and the patient's age and weight. It is usually administered every 6 to 8 hours. Common side effects include nausea, vomiting, diarrhea, and allergic reactions. Serious side effects, such as severe skin reactions and allergic reactions, can occur but are rare.

Ampicillin/sulbactam should be used with caution in patients with a history of allergic reactions to penicillin or other beta-lactam antibiotics. It is also important to complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished. Patients should inform their healthcare provider about all medications, including over-the-counter drugs and herbal supplements, to avoid potential interactions.