amideissas

Amideissas is a term encountered only sporadically in online discussions and in a few preprints, and it does not correspond to a formally recognized enzyme class in the IUBMB nomenclature. The word appears to combine “amide” with a plural suffix, but its precise intended meaning varies by source. As a result, there is no consensus on definition, scope, or diagnostic features.

Possible interpretations include: (a) a broad, informal reference to enzymes that act on amide bonds, such as amidases that hydrolyze primary amides to carboxylic acids and ammonia, or amidotransferases that transfer amide groups; or (b) a speculative or proposed subclass of biocatalysts capable of reversible amide bond formation or transamidation, occasionally described in theoretical or early-stage research. In other contexts, “amideissas” may be used as a mnemonic or placeholder name rather than a defined enzyme family.

Due to the lack of standardization and peer-reviewed definitions, the term should be treated cautiously. In current biochemical literature, researchers typically refer to specific enzyme classes by established names (amidases, amidotransferases, ligases, isomerases) rather than using “amideissas.”

See also: amidases, amidotransferases, transamidation, enzyme nomenclature.