amalo16glukosidasi

Amalo16glukosidasi is an enzyme that plays a role in carbohydrate metabolism. Its name suggests its function: it catalyzes the hydrolysis of an alpha-1,6 glycosidic bond. This specific type of bond is found in branched polysaccharides like glycogen and amylopectin. By breaking these linkages, amalo16glukosidasi releases glucose units, making them available for energy production within cells. It is a type of debranching enzyme. In humans, this enzyme, also known as alpha-amylase or glycogen debranching enzyme, is crucial for the breakdown of stored glycogen in the liver and muscles. Deficiencies in amalo16glukosidasi can lead to glycogen storage diseases, which are characterized by the abnormal accumulation of glycogen in various tissues, causing a range of health problems. The enzyme's activity is essential for maintaining glucose homeostasis and providing energy during fasting periods. Its precise mechanism involves the addition of a water molecule to cleave the alpha-1,6 bond, yielding two smaller carbohydrate chains.