aldoketoreduktaser
Aldoketoreduktases are a superfamily of oxidoreductase enzymes. These enzymes catalyze the reduction of aldehydes and ketones to alcohols, and also the oxidation of alcohols to aldehydes and ketones. This reaction typically involves the cofactor NADPH or NADH, which acts as a hydride donor. Aldoketoreduktases are found in a wide variety of organisms, including bacteria, fungi, plants, and animals.
In humans, aldoketoreduktases play important roles in several metabolic pathways. For example, they are involved in
The mechanism of action for aldoketoreduktases involves the binding of the substrate and the cofactor to the