Y184F
Y184F indicates a missense mutation in which the amino acid tyrosine (Y) at position 184 is replaced by phenylalanine (F) in a protein sequence. The notation is used in genetics, biochemistry, and structural biology to describe single-residue substitutions.
This change is chemically conservative: tyrosine and phenylalanine both have bulky aromatic rings, but tyrosine bears
The functional impact is context-dependent. If residue 184 lies near an active site, substrate-binding pocket, or
In literature, Y184F has been observed in various proteins; its significance is determined by structural data