Vortexers

Vortexers, more commonly known as vortex mixers, are laboratory devices designed to mix liquids in containers by producing a vortex. They are used to resuspend pellets, mix reagents, lyse cells, or homogenize samples in small volumes, typically in microcentrifuge tubes, PCR tubes, or small vials. The basic idea is to impart a rapid, swirling motion to the liquid so that its surface forms a characteristic vortex.

Most vortexers operate in one of two ways. Platform-based models hold a tube or tray on a platform that moves in a circular orbit, forcing the liquid to swirl and form a vortex at the surface. Probe-based or wand-style models use a moving shaft or attachment that directly agitates the liquid inside the tube. The choice between platform and probe designs depends on the sample type, volume, and compatibility with existing lab hardware.

Operating parameters are adjustable on many models. Speeds are typically given in revolutions per minute and can range from a few hundred up to several thousand. Some units offer adjustable orbit size or amplitude, and many can be combined with temperature control or heat blocks for sample integrity. Accessories such as adapters for various tube formats, separators, or containers aid in handling different vessel shapes and volumes.

Applications span routine molecular biology, biochemistry, and clinical labs, including quick resuspension of viral or bacterial pellets, complete mixing of enzyme reactions, and uniform sample preparation prior to analysis. While highly effective for small volumes, vortexers are not suitable for large-scale mixing and may generate aerosols with certain materials, so appropriate safety precautions and containment procedures should be observed.

In practice, vortexers are a staple for rapid, gentle, and repeatable mixing of small-volume samples, offering a simple solution to achieve uniform liquid contact without manual shaking.