Tubulavirales

Tubulavirales is an order of negative-sense single-stranded RNA viruses. Viruses in this order have genomes that are typically monopartite, meaning they consist of a single RNA molecule. The virions are often rod-shaped or filamentous in appearance, hence the name "tubulo" referring to tubes. These viruses infect a wide range of hosts, including plants, fungi, and insects.

The replication cycle of tubulaviruses involves the viral RNA-dependent RNA polymerase transcribing the negative-sense genome into positive-sense mRNA molecules, which are then translated into viral proteins. The genome is also replicated to produce new negative-sense RNA genomes for progeny virions. Assembly of new viruses occurs within the cytoplasm of infected cells.

Tubulavirales includes several families, such as the Rhabdoviridae, which are known for causing diseases in animals and plants, and the Filoviridae, which famously includes the Ebola and Marburg viruses. While distinct in their host ranges and specific disease manifestations, they share fundamental structural and replication characteristics. Research into Tubulavirales is ongoing to understand their complex interactions with hosts and to develop strategies for disease control.