Tablettázás

Tablettázás is a pharmaceutical process used to produce tablets, which are solid dosage forms of medication designed for oral administration. This method involves compressing or shaping powdered or granulated drug substances with excipients into small, typically flat or convex, disc-shaped units. The primary goal of tablettázás is to ensure accurate dosing, enhance stability, facilitate easy swallowing, and improve patient compliance.

The process begins with the formulation stage, where active pharmaceutical ingredients (APIs) are combined with excipients such as fillers, binders, disintegrants, lubricants, and coatings. The mixture is then milled into a uniform powder or granulate, which is fed into tablet presses. These machines compress the material into tablets with a specified weight and hardness.

There are various techniques in tablettázás, including direct compression, where powders are compressed directly into tablets, and wet or dry granulation, which involves forming granules to improve flowability and compressibility. Coating processes can also be applied to modify the surface properties of tablets, such as for taste masking, controlled release, or protection from environmental factors.

Quality control in tablettázás involves checking parameters like weight variation, friability, hardness, disintegration time, and dissolution rate. The process must adhere to pharmaceutical standards and Good Manufacturing Practices (GMP) to ensure safety and efficacy.

This method is widely used due to its efficiency, scalability, and ability to produce a variety of formulations. Overall, tablettázás plays a vital role in modern medicine by providing a reliable and convenient form for delivering medications to patients.