TGFBR16A
TGFBR2 is a gene that encodes a transmembrane serine/threonine receptor kinase involved in the transforming growth factor-beta (TGF-ß) signaling pathway. The gene is located on the short arm of chromosome 1 in humans. Variation in the TGFBR2 gene has been associated with an increased risk of several types of cancer, including colorectal, breast, and ovarian cancer. The protein product of the TGFBR2 gene is a key component of the TGF-ß receptor complex, which plays a crucial role in cellular growth and differentiation.
The TGF-ß signaling pathway is a complex signaling cascade that regulates various cellular processes, including cell
Studies have also linked the TGFBR2 gene to the development of fibrosis and other inflammatory disorders. In
Overall, the TGFBR2 gene is an important component of the TGF-ß signaling pathway, and alterations in this