Syöttösolut

Syöttösolut, often translated as "input cells" or "feeder cells" in English, are a concept primarily used in the field of cell culture and biotechnology. They refer to cells that are intentionally cultured alongside other cells to provide essential support, nutrients, or growth factors. These supporting cells are not the primary cells of interest for a particular experiment or application but are crucial for the survival, proliferation, or differentiation of the target cells.

The use of syöttösolut is widespread in various research areas. For example, in stem cell research, feeder cells are frequently employed to maintain the pluripotency of embryonic stem cells. These feeder cells, often fibroblasts derived from mouse or human tissues, secrete soluble factors and provide a matrix that mimics the natural stem cell niche, preventing premature differentiation. Similarly, in the cultivation of certain primary cells that are difficult to grow *in vitro*, syöttösolut can provide necessary trophic support, increasing cell yield and viability.

Beyond stem cells, syöttösolut find application in the expansion of lymphocytes for immunotherapy, where they can stimulate lymphocyte proliferation and enhance their anti-tumor activity. They can also be used in the production of certain viruses or therapeutic proteins, where their metabolic activity or secreted products are beneficial for the production process. The choice of syöttösolut depends heavily on the specific requirements of the target cells and the intended application, with careful consideration given to their origin, species, and preparation method to ensure optimal support without interfering with downstream analysis or applications.