Syöttösolujen

Syöttösolujen, often translated as "input cells" or "feeder cells" in English, refers to a type of cell used in biological research, particularly in cell culture and stem cell biology. These cells are typically derived from a non-stem cell source and are cultured alongside other cells, such as stem cells, to provide essential support for their survival, proliferation, and differentiation.

The primary function of syöttösolujen is to create a suitable microenvironment for the cells they support. This microenvironment can include the secretion of growth factors, extracellular matrix components, and other signaling molecules that are crucial for maintaining the stemness of pluripotent stem cells or directing the differentiation of progenitor cells. They can also help to clear waste products and provide physical support.

Commonly used syöttösolujen include fibroblasts, such as mouse embryonic fibroblasts (MEFs), and various types of stromal cells. The specific type of syöttösolujen used can influence the behavior and developmental potential of the cells they support, making their selection an important consideration in experimental design. The use of syöttösolujen has been instrumental in advancing research in areas like regenerative medicine, developmental biology, and disease modeling.