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Swertiamarin

Swertiamarin is a natural product belonging to the class of secoiridoid glycosides. It is found in several plant species of the Gentianaceae, most notably in Swertia chirayita (swertia or Indian gentian) and other Swertia species, as well as in related genera. Swertiamarin is the glucoside of swertianic acid, consisting of an iridoid-type aglycone with a β-D-glucosyl unit attached by a glycosidic bond.

Biosynthesis and role: In plants, swertiamarin arises via the iridoid biosynthetic pathway and contributes to the

Uses and research: Swertiamarin has been investigated in preclinical studies for a range of pharmacological activities,

Safety and availability: There are limited data on human safety and pharmacokinetics. Swertiamarin is not an

bitter
taste
of
the
plant.
It
also
serves
as
a
metabolic
intermediate
in
the
production
of
related
secoiridoids
in
the
plant's
defense
arsenal.
including
anti-inflammatory,
antimicrobial,
antioxidative,
and
hepatoprotective
effects.
Most
results
come
from
in
vitro
experiments
or
animal
models;
clinical
evidence
is
not
established.
approved
medicine
and
is
primarily
encountered
as
a
constituent
of
traditional
herbal
preparations
or
as
a
research
chemical
in
phytochemical
studies.