Srat

Srat, also known as SRAT or SRA-TR, is a protein found in many organisms, playing a role in various cellular processes. It is a member of the DEAD-box family of RNA helicases. These proteins are characterized by conserved amino acid sequences, including the Asp-Glu-Ala-Asp (DEAD) motif, which is crucial for their ATP-dependent unwinding of RNA duplexes.

In humans, SRAT is involved in regulating gene expression and is thought to participate in processes such as transcription, translation, and RNA splicing. It interacts with a multitude of other proteins and RNA molecules, forming complex regulatory networks. Its precise functions can vary depending on the cellular context and the specific RNA targets it binds to. Research has indicated its involvement in cellular stress responses and maintaining genomic stability.

Studies have explored the role of SRAT in the development of certain diseases, including cancer, where its dysregulation can contribute to uncontrolled cell growth. Understanding the molecular mechanisms of SRAT is an ongoing area of research, aiming to shed light on its broad cellular functions and its potential as a therapeutic target. The protein's diverse interactions and roles highlight its importance in maintaining cellular homeostasis.