Spermatogonioiden

Spermatogonioiden, also known as spermatogonia, are immature germ cells that give rise to mature sperm cells in males. They are found in the seminiferous tubules of the testes. Spermatogonia are diploid cells, meaning they contain two sets of chromosomes. They undergo cell division, a process called mitosis, to produce more spermatogonia and also to differentiate into specialized cells that will eventually become sperm.

There are two main types of spermatogonia: type A and type B. Type A spermatogonia are considered stem cells; they are self-renewing and ensure a continuous supply of germ cells throughout a male's reproductive life. They divide mitotically to produce more type A spermatogonia and also type B spermatogonia. Type B spermatogonia are committed to differentiation. They divide mitotically to produce cells that will then enter meiosis, the specialized cell division process for producing gametes.

The development of spermatogonia into sperm is a complex process called spermatogenesis. This process begins at puberty and continues throughout a man's life. Spermatogonia are located in the basal compartment of the seminiferous tubules, where they are protected by the blood-testis barrier. This barrier is crucial for maintaining the immune privilege of the developing sperm cells and preventing autoimmune reactions. As spermatogenesis progresses, cells move towards the lumen of the seminiferous tubule, undergoing a series of transformations.