Sertolisoluakudoksessa

Sertolisoluakudoksessa refers to the tissue composed of Sertoli cells. Sertoli cells are a type of somatic cell found in the seminiferous tubules of the testes in males. They play a crucial role in spermatogenesis, the process of sperm production. These cells are large, irregular in shape, and extend from the basal lamina to the lumen of the seminiferous tubule. Sertoli cells form a barrier, known as the blood-testis barrier, which separates the germ cells from the bloodstream and immune system. This barrier is essential for protecting the developing sperm cells from immune attack and maintaining a specialized microenvironment conducive to meiosis.

The functions of Sertoli cells are multifaceted. They provide structural support to the germ cells, nurturing them throughout their development. Sertoli cells secrete various factors, including androgen-binding protein (ABP), inhibin, and growth factors, which are vital for regulating spermatogenesis. They also phagocytose residual bodies and degenerating germ cells, helping to maintain the integrity of the seminiferous epithelium. The coordinated activity of Sertoli cells is indispensable for the continuous production of viable sperm.