Sec10EXOC5

Sec10EXOC5, also known as EXOC5 or the Exocyst complex component 10, is a protein encoded by the EXOC5 gene. This gene is part of the exocyst complex, a highly conserved protein complex essential for cell polarity and exocytosis in eukaryotic cells. The exocyst complex is a hetero-octameric structure that plays a crucial role in the targeted delivery of secretory vesicles to specific sites on the plasma membrane.

EXOC5 is one of the eight subunits of the exocyst complex. It is known to interact with other exocyst components, contributing to the overall structure and function of the complex. The exocyst complex is involved in a variety of cellular processes, including vesicle tethering and fusion during exocytosis, which is the process by which cells release molecules to the outside. This process is vital for nutrient uptake, waste removal, and cell signaling.

Research on Sec10EXOC5 has explored its involvement in cell growth, migration, and the development of various tissues. Dysregulation of exocyst components, including EXOC5, has been implicated in diseases such as cancer, where abnormal exocytosis can contribute to tumor progression and metastasis. Understanding the precise role of Sec10EXOC5 within the exocyst complex and its interactions with other cellular machinery is an ongoing area of research.