Sadenosüülmetioniin

Sadenosüülmetioniin, also known as S-adenosylmethionine or SAMe, is a naturally occurring compound found in all living cells. It is synthesized from the amino acid methionine and adenosine triphosphate (ATP). SAMe plays a crucial role in numerous biochemical reactions within the body, acting as a methyl group donor.

This methyl group transfer is vital for various metabolic processes, including DNA synthesis and repair, protein function, and the synthesis of neurotransmitters like serotonin and dopamine. SAMe is also involved in the production of creatine, a molecule important for energy storage in muscles, and in the synthesis of polyamines, which are essential for cell growth and division.

The body produces SAMe endogenously, but its levels can be influenced by factors such as diet, age, and certain medical conditions. Due to its involvement in methylation pathways and its potential impact on neurotransmitter synthesis, SAMe has been studied for its potential therapeutic applications. It is often used as a dietary supplement and has been investigated for its effects on mood disorders, osteoarthritis, and liver health. However, the scientific evidence supporting these uses varies, and further research is ongoing.