SPFHdomains
SPFHdomains refers to a family of protein domains found in eukaryotes. These domains are characterized by a conserved amino acid sequence and a specific three-dimensional structure. Proteins containing SPFHdomains are involved in a variety of cellular processes, including cell adhesion, signaling, and development. The SPFHdomain is named after its presence in several well-studied proteins, such as the yeast protein Spo20, the human protein p53, and the plant protein Hypothetical protein HIPP12B.
The SPFHdomain typically consists of a beta-sheet core flanked by alpha-helices. This structural motif allows SPFHdomain-containing
Research into SPFHdomains is ongoing, with scientists working to fully elucidate their diverse roles in cellular