SPDEF
SPDEF is a protein that in humans is encoded by the SPDEF gene. It belongs to the BTB family of transcription factors, which are characterized by the presence of a BTB domain. This domain is responsible for protein-protein interactions and functions as a substrate recognition site for E3 ubiquitin ligases.
The SPDEF gene is located on chromosome 20 in humans, and it consists of 9 exons. It
Studies have shown that SPDEF plays a role in the regulation of transcription. It has been implicated
Mutations in the SPDEF gene have been associated with several human diseases, including bronchial asthma, which
Research has also explored the potential of SPDEF as a therapeutic target in various diseases. Mutations that
Further research is needed to fully understand the functions and mechanisms of SPDEF, particularly in the context