Reagoinniksi

Reagoinniksi is a theoretical concept in chemistry describing a class of mediating agents that can act both as reagents and as catalysts across successive steps in a reaction sequence. In the proposed view, reagoinniksi participate in an initial transformation, form an intermediate state, and then regenerate to enable the next step, potentially reducing the need for separate reagents and improving overall step economy.

Originating as a neologism in informal discussions and some preprint glossaries, the term combines a root related to reaction with a suffix that denotes a functional role. It is not yet part of formal, peer‑reviewed nomenclature, and its usage varies across sources.

In terms of proposed properties, a reagoinniksi is envisioned to be compatible with multiple substrates, capable of reversible or regenerable interactions, and able to bridge reaction steps without being consumed in the overall sequence. Possible platforms discussed include metal–ligand clusters, organocatalytic species, or supramolecular assemblies that can host transient intermediates and then release them for subsequent transformations.

Potential benefits of employing reagoinniksi include shortened synthetic sequences, reduced solvent and reagent waste, and simplified purification. Challenges include precise design to ensure selectivity and compatibility, robust regeneration across cycles, and acceptance within established chemical nomenclature.

Status and reception: at present, reagoinniksi remains a speculative concept and is not a widely recognized category in standard chemical literature. It may appear in theoretical discussions or as a heuristic for thinking about multi-step mediation rather than as a defined, experimental class.

See also: catalysis, reagent, cascade reaction, tandem reaction, reaction mechanism.